AJR AJR Integrative Imaging Dec 2008 articles
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American Journal of Roentgenology, Vol 103, 800-822, Copyright © 1968 by American Roentgen Ray Society


SECOND PRIMARY NEOPLASMS IN CHILDREN

M. TEFFT M.D.1, G. F. VAWTER M.D.2, and A. MITUS M.D.3

1 From The Children's Cancer Research Foundation and from the Department of Radiology, of The Children's Hospital Medical Center, Boston, Massachusetts and from the Department of Radiology, of the Harvard Medical School, Boston, Massachusetts
2 From The Children's Cancer Research Foundation and from the Department of Pathology, of The Children's Hospital Medical Center, Boston, Massachusetts and from the Department of Pathology, of the Harvard Medical School, Boston, Massachusetts
3 From the Department of Pediatrics of the Harvard Medical School, Boston, Massachusetts

The records of the Children's Hospital Medical Center were reviewed for the years 1938 to 1963. Case histories are presented of children treated for malignancies who developed second tumors, lymphomas or leukemia.

Our study revealed that the approximate incidence of double primary tumors in children with malignancy, seen at our Center, was 0.5 per cent, or 5.0 per cent of all children who received radiation in doses in excess of 1,000 rads and who have survived free of disease at least 2 years.


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