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Lymphosarcoma of the colon is an uncommon disease entity. The roentgenographic findings which have been most helpful in differentiating lymphosarcoma from other colonic disorders include the presence of: diffuse nodular lesions with irregular margins, the latter suggesting infiltration of the bowel wall; bulky ulcerating masses extending over a long segment of the colon; an association of nonuniform submucosal nodules and marked haustral thickening and circumferential narrowing of the colonic lumen with intact mucosa.
Finally, any colonic lesion in a patient with known systemic lymphoma is suspect for being lymphosarcoma of the colon.
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