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American Journal of Roentgenology, Vol 130, Issue 1, 7-11
Copyright © 1978 by American Roentgen Ray Society

Articles

Prostaglandin E1 (PGE1) in angiography of tumors of the extremities

K Jonsson, LA de Santos, S Wallace, and JH Anderson

Prostaglandin E1 (PGE1) is a potent vasodilator. The value of this agent as an adjuvant in angiography of tumors of the extremities was evaluated in 10 patients. Except in one case involving a hemangioma, the diagnostic information concerning tumor vascularity and delineation of the extent of disease decreased after the use of PGE1. The visualization of small normal muscular arteries was improved. Therefore, the effect of PGE1 may be to preferentially increase the blood flow in normal tissues relative to the tumor. PGE1 seems to be of little value in enhancing the angiographic demonstration of neoplasms of the extremity.
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Copyright © 1978 by the American Roentgen Ray Society.