American Journal of Roentgenology, Vol 130, Issue 4, 747-750
Copyright © 1978 by American Roentgen Ray Society
Tween 80/diatrizoate enemas in bowel obstruction
BP Wood
and
RW Katzberg
Although successful treatment of meconium ileus with Gastrografin enema has been attributed to the hypertonicity of this material, Tween 80, present in a 0.75% concentration, may be its most effective component. Tween 80 acts as a surface-active substance and stool emulsifier. An enema solution of 1%-2% Tween 80 and isotonic sodium diatrizoate has been effective in the relief of meconium or fecal mass obstruction in infants and children.