MR imaging of paragangliomas

MR imaging of 15 paragangliomas in 10 patients was compared with CT of 13 of the lesions in eight patients. All lesions were confirmed with angiography. All lesions were detected by MR and CT with the exception of one small glomus tympanicum tumor that was seen only in retrospect with MR. CT better demonstrated subtle osseous changes of the skull base and the relation of the tumor to the middle ear structures. MR better demonstrated the relation of the tumor to the adjacent internal jugular vein and carotid artery. The paragangliomas had a characteristic MR appearance based on their vascularity. Serpiginous areas of signal void representing high vascular flow were interspersed among areas of high signal intensity caused by slowly flowing blood and tumor cells. This "salt-and-pepper" pattern was seen in all lesions greater than 2 cm in maximal dimension. MR was therefore able to accurately characterize the tumors as highly vascular. Multiplanar imaging and good tissue contrast and anatomic detail permitted display of the relations of these neoplasms to surrounding carotid sheath vessels and to intracranial structures better than did CT. In this experience, the MR appearance of paragangliomas was quite characteristic and differed markedly from meningiomas, neuromas, and metastatic disease of the skull base.
CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				S. Arya, V. Rao, S. Juvekar, and A.K. Dcruz Carotid Body Tumors: Objective Criteria to Predict the Shamblin Group on MR Imaging AJNR Am. J. Neuroradiol., August 1, 2008; 29(7): 1349 - 1354. [Abstract] [Full Text] [PDF]

				F. Neves, L. Huwart, G. Jourdan, D. Reizine, P. Herman, E. Vicaut, and J.P. Guichard Head and Neck Paragangliomas: Value of Contrast-Enhanced 3D MR Angiography AJNR Am. J. Neuroradiol., May 1, 2008; 29(5): 883 - 889. [Abstract] [Full Text] [PDF]

				S Bhatt, S Vanderlinde, R Farag, and V S Dogra Pararectal paraganglioma Br. J. Radiol., October 1, 2007; 80(958): e253 - e256. [Abstract] [Full Text] [PDF]

				K. Y. Lee, Y.-W. Oh, H. J. Noh, Y. J. Lee, H.-S. Yong, E.-Y. Kang, K. A. Kim, and N. J. Lee Extraadrenal paragangliomas of the body: imaging features. Am. J. Roentgenol., August 1, 2006; 187(2): 492 - 504. [Abstract] [Full Text] [PDF]

				K. M. Elsayes, V. R. Narra, J. R. Leyendecker, I. R. Francis, J. S. Lewis Jr., and J. J. Brown MRI of Adrenal and Extraadrenal Pheochromocytoma Am. J. Roentgenol., March 1, 2005; 184(3): 860 - 867. [Full Text] [PDF]

				R. van den Berg, B. M. Verbist, B. J. A. Mertens, A. G. L. van der Mey, and M. A. van Buchem Head and Neck Paragangliomas: Improved Tumor Detection Using Contrast-Enhanced 3D Time-of-Flight MR Angiography As Compared with Fat-Suppressed MR Imaging Techniques AJNR Am. J. Neuroradiol., May 1, 2004; 25(5): 863 - 870. [Abstract] [Full Text] [PDF]

				F. Bonneville, J.-L. Sarrazin, K. Marsot-Dupuch, C. Iffenecker, Y.-S. Cordoliani, D. Doyon, and J.-F. Bonneville Unusual Lesions of the Cerebellopontine Angle: A Segmental Approach RadioGraphics, March 1, 2001; 21(2): 419 - 438. [Abstract] [Full Text] [PDF]

				R. van den Berg, M. N.J.M. Wasser, A. P.G. van Gils, A. G.L. van der Mey, J. Hermans, and M. A. van Buchem Vascularization of Head and Neck Paragangliomas: Comparison of Three MR Angiographic Techniques with Digital Subtraction Angiography AJNR Am. J. Neuroradiol., January 1, 2000; 21(1): 162 - 170. [Abstract] [Full Text] [PDF]

				A. B. Rao, K. K. Koeller, and C. F. Adair From the Archives of the AFIP: Paragangliomas of the Head and Neck: Radiologic-Pathologic Correlation RadioGraphics, November 1, 1999; 19(6): 1605 - 1632. [Abstract] [Full Text] [PDF]