HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Brunereau, L. Articles by Rouleau, P. Search for Related Content PubMed PubMed Citation Articles by Brunereau, L. Articles by Rouleau, P. Social Bookmarking                      What's this?

Uterine Artery Embolization in the Primary Treatment of Uterine Leiomyomas

Technical Features and Prospective Follow-Up with Clinical and Sonographic Examinations in 58 Patients

¹ Service de Radiologie Adultes (Pr Rouleau), Hôpital Bretonneau, CHRU Tours, F.37044 Tours, Cedex 01, France.
² Service de Neuroradiologie (Pr Herbreteau), Hôpital Bretonneau, Cedex 01, France.
³ Départment de Gynécologie-Obstétrique (Pr Lansac), Hôpital Bretonneau, Cedex 01, France.
⁴ Service de Médecine Nucléaire et Ultrasons (Pr Pourcelot), Hôpital Bretonneau, Cedex 01, France.

OBJECTIVE. The purpose of this study was to analyze the technical features of uterine artery embolization and to evaluate the effectiveness of this method as the primary treatment of uterine leiomyomas in a series of 58 patients monitored by clinical and sonographic examinations.

SUBJECTS AND METHODS. Fifty-eight women (age range, 33-65 years; mean age, 44.5 years) with symptoms caused by uterine leiomyomas (abnormal bleeding, bulk-related symptoms, pelvic pain) were included in this prospective study. We performed embolization with a single catheter using the single-femoral artery approach, injection of particles (150-250 mm), and an absorbable gelatin sponge. Postprocedural pain was assessed using a visual analog scale. Systematic follow-up included clinical and sonographic examinations at 3 months for 58 patients, at 6 months for 46 patients, at 1 year for 27 patients, and at 2 years for seven patients.

RESULTS. Embolization was performed without problems in 84% of the patients. Post-procedural pain control was excellent in 90% of the patients. In most patients, symptoms were improved or had resolved at 3 months (90%), 6 months (92%), and 1 year (93%), and all patients were symptom-free at 2 years. Clinical failure of treatment occurred in only two patients (3%). Progressive reduction in leiomyoma size was revealed during sonographic follow-up, and new leiomyomas were seen in one patient at 2 years.

CONCLUSION. Uterine artery embolization is an endovascular method for the treatment of uterine leiomyomas that is clinically effective in most patients and that induces a progressive reduction in the size of the largest leiomyomas.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				A. Raikhlin, M. O. Baerlocher, and M. R. Asch Uterine fibroid embolization: CME update for family physicians Can Fam Physician, February 1, 2007; 53(2): 250 - 256. [Abstract] [Full Text] [PDF]

				S. Ghai, D. K. Rajan, M. S. Benjamin, M. R. Asch, and S. Ghai Uterine Artery Embolization for Leiomyomas: Pre- and Postprocedural Evaluation with US RadioGraphics, September 1, 2005; 25(5): 1159 - 1172. [Abstract] [Full Text] [PDF]

				I. Pinto, P. Chimeno, A. Romo, L. Paul, J. Haya, M. A. de la Cal, and J. Bajo Uterine Fibroids: Uterine Artery Embolization versus Abdominal Hysterectomy for Treatment--A Prospective, Randomized, and Controlled Clinical Trial Radiology, February 1, 2003; 226(2): 425 - 431. [Abstract] [Full Text] [PDF]

				B. McLucas, R. Perrella, S. Goodwin, L. Adler, and J. Dalrymple Role of Uterine Artery Doppler Flow in Fibroid Embolization J. Ultrasound Med., February 1, 2002; 21(2): 113 - 120. [Abstract] [Full Text] [PDF]

				C. J. Muniz, A. C. Fleischer, E. F. Donnelly, and M. J. Mazer Three-dimensional Color Doppler Sonography and Uterine Artery Arteriography of Fibroids: Assessment of Changes in Vascularity Before and After Embolization J. Ultrasound Med., February 1, 2002; 21(2): 129 - 133. [Abstract] [Full Text] [PDF]

				T. Katsumori, K. Nakajima, T. Mihara, and M. Tokuhiro Uterine Artery Embolization Using Gelatin Sponge Particles Alone for Symptomatic Uterine Fibroids: Midterm Results Am. J. Roentgenol., January 1, 2002; 178(1): 135 - 139. [Abstract] [Full Text] [PDF]

				L. A. Kory, L. Brunereau, D. Herbreteau, and P. Rouleau A Question of Scale Am. J. Roentgenol., June 1, 2001; 176 (6): 1597 - 1598. [Full Text] [PDF]