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1
Department of Radiology, St. Marianna University School of Medicine, 2-16-1
Sugao, Miyamae-Ku, Kawasaki City, 216-8511 Japan.
2
Department of Radiology, Osaka University School of Medicine, 2-2, Yamada-oka,
Suita Osaka, 5650871 Japan.
OBJECTIVE. The objective of this research was to compare high-resolution CT findings of bronchiolitis obliterans with organizing pneumonia (BOOP) with those of chronic eosinophilic pneumonia (CEP) and to determine whether high-resolution CT can differentiate the two.
MATERIALS AND METHODS. We retrospectively reviewed high-resolution CT scans of 38 patients with BOOP and 43 patients with CEP. Without knowledge of the diagnosis, two radiologists evaluated the frequency and distribution of high-resolution CT findings in both groups of patients and made a diagnosis using a three-point scale of confidence.
RESULTS. Nodules, nonseptal linear or reticular opacities, and
bronchial dilatation were significantly more common in BOOP than in CEP (31.6%
vs. 4.7%, p < 0.005; 44.7% vs. 9.3%, p < 0.001; and
57.9% vs. 25.6%, p < 0.005, respectively). Septal line thickening
was more frequent in CEP than in BOOP (72.1% vs. 39.5%, p <
0.005). Peribronchial distribution of consolidation was more frequent in BOOP
than in CEP (28.9% vs. 9.3%, p < 0.05). A correct diagnosis was
made in 69.7% of cases, and the diagnostician was confident in 21.7%.
Interobserver agreement was good (
= 0.6).
CONCLUSION. Although several of the high-resolution CT findings of BOOP and CEP are different, these diseases are differentiated with confidence in only a small percentage of cases.
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