| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Department of Radiology, University "Federico II," Via Pansini 5,
Via Manzoni 214/0, Napoli 80123, Italy.
2 Department of Radiology, New York University School of Medicine, New York,
NY.
OBJECTIVE. The purpose of our study was to determine the diagnostic value of single-phase MDCT in patients with suspected pancreatic carcinoma.
SUBJECTS AND METHODS. Seventy-one patients (41 men, 30 women; mean age, 63 years; range, 29-80 years) with suspected pancreatic tumor underwent MDCT. Scanning was performed on an MDCT scanner with 0.5-sec gantry rotation and acquisition of 4 slices per rotation. Unenhanced scanning was followed by one set of scanning in the caudocranial direction from the inferior hepatic margin to the diaphragm with a scanning delay of 60 sec after the IV injection of 150 mL of contrast material delivered at 3 mL/sec. Two reviewers independently scored images in a blinded fashion for the presence of tumor and assessment of resectability. Receiver operating characteristic analysis was performed.
RESULTS. A final histopathologic diagnosis derived from surgical findings was obtained in 42 patients; in the remaining 29 patients, percutaneous fine-needle aspiration biopsy coupled with a 1-year clinical follow-up to determine development of local, regional or distant neoplasm served as gold standard proof of diagnosis. Final diagnosis was pancreatic cancer in 40 patients (27 ductal adenocarcinoma, nine mucinous cystoadenocarcinoma, two neuroendocrine tumors, one lymphoma, and one papillary cystoadenocarcinoma) and chronic pancreatitis in 31. The mean tumor size was 2.4 cm (range, 4-1 cm). Values for the area under the curve (Az) for the assessment of tumor detection were 0.97 for reviewer 1 and 0.96 for reviewer 2 (p = not significant). Az values for tumor resectability were 0.90 for reviewer 1 and 0.90 for reviewer 2 (p = not significant). No statistically significant differences were observed between superior mesenteric artery and vein opacification with the hepatic parenchyma enhanced at a time closer to the peak hepatic enhancement, optimizing the detection of hepatic lesions.
CONCLUSION. Thin-section single-phase MDCT is an accurate technique for the diagnosis and assessment of resectability in patients with a suspected pancreatic neoplasm. This technique provides optimal tumor-to-pancreas contrast and maximal pancreatic parenchymal and peripancreatic vascular enhancement. It allows visualization of the entire liver and the whole upper abdomen during the portal phase for accurate identification of liver metastases and peritoneal seeding.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  H. Kondo, M. Kanematsu, S. Goshima, T. Miyoshi, Y. Shiratori, M. Onozuka, N. Moriyama, and K. T. Bae MDCT of the Pancreas: Optimizing Scanning Delay with a Bolus-Tracking Technique for Pancreatic, Peripancreatic Vascular, and Hepatic Contrast Enhancement Am. J. Roentgenol., March 1, 2007; 188(3): 751 - 756. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Ichikawa, S. M. Erturk, H. Sou, H. Nakajima, T. Tsukamoto, U. Motosugi, and T. Araki MDCT of pancreatic adenocarcinoma: optimal imaging phases and multiplanar reformatted imaging. Am. J. Roentgenol., December 1, 2006; 187(6): 1513 - 1520. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Imbriaco Reply Am. J. Roentgenol., January 1, 2006; 186(1): 267 - 267. [Full Text] [PDF]
|
|
|
|
|
|
S. M. Erturk Value of the Single-Phase Technique in MDCT Assessment of Pancreatic Tumors Am. J. Roentgenol., January 1, 2006; 186(1): 266 - 267. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
