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DOI:10.2214/AJR.04.1546
AJR 2005; 185:1335-1341
© American Roentgen Ray Society

Clinical Observations

Posttransplantation Lymphoproliferative Disorder in Pediatric Recipients of Solid Organ Transplants: Timing and Location of Disease

Gregory E. Wilde1,2, Daniel J. Moore2,3 and Richard D. Bellah2

1 Present address: Department of Radiology, Christiana Hospital, 4755 Ogletown-Stanton Rd., Newark, DE 19713.
2 Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA.
3 Present address: Department of Pediatrics, Vanderbilt Children's Hospital, Nashville, TN.

OBJECTIVE. The objective of our study was to correlate the location of radiologic presentation and time to onset of posttransplantation lymphoproliferative disorder (PTLD) with the allograft type received in a population of pediatric heart, lung, liver, kidney, and bone marrow transplant recipients.

CONCLUSION. Symptomatic PTLD in children manifests earliest in lung recipients and can involve any organ system. However, PTLD in the thorax is most common after lung transplantation, and PTLD in the abdomen most commonly follows kidney transplantation.


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