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DOI:10.2214/AJR.04.1599
AJR 2005; 185:1531-1539
© American Roentgen Ray Society


Pictorial Essay

Idiopathic Pulmonary Fibrosis: Spectrum of High-Resolution CT Findings

Carolina Althoff Souza1, Nestor L. Müller1, Julia Flint2, Joanne L. Wright2 and Andrew Churg2

1 Department of Radiology, Vancouver General Hospital, University of British Columbia, 899 W. 12th Ave., Vancouver, BC V5Z 1M9, Canada.
2 Department of Pathology, Vancouver General Hospital, University of British Columbia, Vancouver, BC V5Z 1M9, Canada.

OBJECTIVE. Characteristic high-resolution CT (HRCT) findings of idiopathic pulmonary fibrosis (IPF) include reticulation, architectural distortion, and honeycombing involving mainly the lung periphery and the lower lobes. In 50% of IPF patients, HRCT is nonspecific. This article illustrates the HRCT findings of IPF correlating with the pathology.

CONCLUSION. The spectrum of HRCT manifestations varies from typical findings that allow confident diagnosis to atypical patterns mimicking other diseases, including predominance of ground-glass opacity, consolidation, nodules, and atypical distribution of lesions.


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I. Noth and F. J. Martinez
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