| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Original Research |
1 Department of Diagnostic Imaging, Rambam Medical Center, Haifa, Israel.
2 Department of Cardiology, Rambam Medical Center, Haifa, Israel.
OBJECTIVE. The purpose of our study was to prospectively evaluate the usefulness of CT coronary angiography versus invasive coronary angiography for the detection of clinically significant coronary artery disease in patients hospitalized for acute chest pain syndrome.
SUBJECTS AND METHODS. Sixty-six consecutive patients (52 men and 14 women; average age, 57 ± 11 [SD] years) who were hospitalized for acute chest pain syndrome underwent CT coronary angiography and invasive coronary angiography within an average time interval of 4 days. ECG-gated CT coronary angiography was performed with a 16-MDCT scanner (0.42-sec rotation time, 16 x 0.75 mm detector collimation). Beta-blockers were not administered routinely, and thus the average heart rate was 71 ± 11 beats per minute. CT coronary angiographic images were evaluated concurrently by two radiologists, who were blinded to invasive coronary angiography results, for stenoses having a diameter of 50% or more, using a 15-segment classification, including all segments 2 mm or more in diameter. The consensus interpretation was compared with results of invasive coronary angiography.
RESULTS. CT coronary angiography was technically successful in 59 patients (89%). After exclusion of 20 (3.1%) of 649 coronary segments, which were classified as nonevaluable by CT coronary angiography, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of CT coronary angiography for identifying significant coronary artery disease in the remaining 629 coronary segments were 80% (68/85), 89% (482/544), 52% (68/130), 97% (482/499), and 87% (550/629), respectively. The overall accuracy for the main vessels (left main, left anterior descending, left circumflex, and right coronary arteries) was 93%, 88%, 86%, and 86%, respectively.
CONCLUSION. CT coronary angiography using a 16-MDCT scanner enables accurate noninvasive detection of significant coronary artery disease in patients hospitalized for acute chest pain syndrome. Furthermore, relative high sensitivity and specificity of CT coronary angiography can be achieved without pharmacologic manipulation of patient heart rates.
Keywords: angiography • chest pain • coronary artery disease • MDCT angiography
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  C. S. White and D. Kuo Chest Pain in the Emergency Department: Role of Multidetector CT Radiology, December 1, 2007; 245(3): 672 - 681. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hamon, R. Morello, J. W. Riddell, and M. Hamon Coronary Arteries: Diagnostic Performance of 16- versus 64-Section Spiral CT Compared with Invasive Coronary Angiography Meta-Analysis Radiology, December 1, 2007; 245(3): 720 - 731. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.M. Lell, H. Ditt, C. Panknin, J.W. Sayre, S.G. Ruehm, E. Klotz, B.F. Tomandl, and J.P. Villablanca Bone-Subtraction CT Angiography: Evaluation of Two Different Fully Automated Image-Registration Procedures for Interscan Motion Compensation AJNR Am. J. Neuroradiol., August 1, 2007; 28(7): 1362 - 1368. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Stable angina who needs revascularisation? DTB, February 1, 2007; 45(2): 12 - 16. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Muhlenbruch, A. H. Mahnken, M. Das, R. Blindt, C. Hohl, J. E. Wildberger, R. W. Gunther, H. P. Kuhl, and R. Koos Evaluation of Aortocoronary Bypass Stents with Cardiac MDCT Compared with Conventional Catheter Angiography Am. J. Roentgenol., February 1, 2007; 188(2): 361 - 369. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
