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MRI of Hepatic Adenomatosis: Initial Observations with Gadoxetic Acid Contrast Agent in Three Patients

¹ Department of Radiology, University Hospital Basel, Basel, Switzerland.
² Present address: Institute of Radiology, Kantonsspital Aarau, Tellstrasse, 5001 Aarau, Switzerland.
³ Department of Gastroenterology, University Hospital Basel, Basel, Switzerland.
⁴ Department of Pathology, University Hospital Basel, Basel, Switzerland.
⁵ Imamed Radiologie Nordwest, Basel, Switzerland.

OBJECTIVE. The purpose of our study was to describe the MR signal characteristics of histologically proven liver adenomatosis in three patients using gadoxetic acid, a newly developed liver-specific MR contrast agent.

CONCLUSION. In all three patients, more than 100 liver adenomas revealed no metabolism of the new liver-specific contrast agent in the delayed phase. Because of absent or strongly reduced intracellular uptake of gadoxetic acid in all adenomas during delayed contrast-enhanced series, differentiation of adenomas from dysplastic or malignant lesions was not possible.

Keywords: abdominal imaging • gadoxetic acid • liver adenomatosis • liver imaging

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