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American Journal of Roentgenology, Vol 95, 557-572, Copyright © 1965 by American Roentgen Ray Society

INTERRUPTION OF AORTIC ARCH

ANATOMIC PATTERNS AND ASSOCIATED CARDIAC MALFORMATIONS

JAMES H. MOLLER M.D.1 and JESSE E. EDWARDS M.D.2

1 Postdoctoral Fellow HE 19,867, National Heart Institute, National lnstitutes of Health, United States Public Health Service
2 From the Departments of Pediatrics and Pathology, University of Minnesota, Minneapolis, Minnesota, and the Department of Pathology, The Charles T. Miller Hospital, St. Paul, Minnesota

One hundred five cases of interruption of the aortic arch (95 from the literature; 10 from personal experience) were reviewed and grouped according to the pattern of the aortic arch. Most of the subjects exhibited congestive cardiac failure while young infants. A classification based on the sites of origin of the subclavian arteries with respect to the site of aortic interruption is presented as a useful guide in the interpretation of angiocardiograms and of levels of arterial oxygen saturations in cases of this malformation.

A review was also made of the intracardiac anomalies that are associated with interruption of the aortic arch.

In 98 cases, a ventricular septal defect coexisted with the interruption of the aortic arch either as an isolated intracardiac anomaly (58 cases) or as part of an anomalous complex (40 cases). In only 6 of 105 cases of interruption of the aortic arch were there no associated intracardiac anomalies. A patent ductus arteriosus was almost universally present. In only 2 patients, each an adult, was the ductus arteriosus found closed.


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