AN EVALUATION OF THE RADIOTHERAPEUTIC MANAGEMENT OF INTRACRANIAL GLIAL TUMORS WITHOUT PRIOR SURGERY

¹ NEW YORK, NEW YORK

A group of 77 patients, clinically diagnosed as having the more malignant glial tumors in which radiotherapy was the sole effective therapeutic agent, is evaluated. If the 12 patients who died within the first month and, therefore, did not complete the proposed course of therapy are excluded, the I year survival rate (24/65; 37 per cent) compares favorably with published results of patients treated with radiotherapy following partial excision.

Treatment volumes in excess of 1,000 cc., or tumor doses above 4,000 rads in 5 weeks, did not alter the prognosis. Postmortem histology obtained in 46 per cent of the cases confirmed the clinical diagnosis in all but 3 instances in those patients who lived less than 12 months, and in all those patients who survived more than I year.

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