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American Journal of Roentgenology, Vol 96, 158-165, Copyright © 1966 by American Roentgen Ray Society

THE VALUE OF CHEMOTHERAPY IN THE IRRADIATION OF OVARIAN CARCINOMA

EMANUEL E. SCHWARTZ M.D.1, DAVID M. SKLAROFF M.D.1, and STANLEY N. LEVICK M.D.2

1 Department of Radiology, University of Virginia School of Medicine, Charlottesville, Virginia
2 Department of Hematology, Albert Einstein Medical Center, and Moss Rehabilitation Home, Philadelphia, Pennsylvania

1. Combined chemotherapy and irradiation has been administered to 58 ovarian carcinoma patients, most of them advanced cases, from 1958 through 1964.

2. Nineteen of 44 patients who received Thio-TEPA plus irradiation still survive as long as 12 to 68 months after the start of treatment.

3. Patients who subsequently developed recurrences usually responded to a second course of chemotherapy.

4. These results, as well as the duration of the original period of remission, are an improvement over those previously obtained without the benefit of chemotherapy at this institution.

5. The additional morbidity associated with this approach is deemed acceptable.


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Copyright © 1966 by the American Roentgen Ray Society.