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American Journal of Roentgenology, Vol 96, 510-518, Copyright © 1966 by American Roentgen Ray Society


LIVER FUNCTION STUDIES IN PATIENTS RECEIVING ENEMAS CONTAINING TANNIC ACID

H. JOACHIM BURHENNE M.D.1, PETER VOGELAAR M.D.1, and ROBERT S. ARKOFF M.D.1

1 From the Departments of Radiology of the Children's Hospital and the University of California School of Medicine, San Francisco, California

Recent reports have emphasized that tannic acid, a time-honored agent in barium enema examinations, may cause severe side reactions.

Studies of liver function in 45 patients indicate the safety of enemas with tannic acid when used in the following dosage: 0.25 per cent tannic acid* in the cleansing enema and 0.5 per cent regular tannic acid in the barium enema mixture.

Since tannic acid appears to have both a safe and a toxic dose range, accurate measurement is of utmost importance. Standardized individual packaging of tannic acid is thus recommended.


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