SIMULTANEOUS PAH, INULIN AND RENOGRAFIN-I¹³¹ RENAL CLEARANCE DETERMINATIONS AND A METHOD FOR CALCULATING RENOGRAFIN CLEARANCE FROM RENOGRAMS IN PATIENTS

¹ From the Departments of Radiology, Urology, and Physiology, Bowman Gray School of Medicine of Wake Forest College, Winston-Salem, North Carolina

1. Even when both ortho-iodo¹³¹-hippuric acid (OI¹³¹HA) and renografin-I¹³¹ renograms are normal qualitatively, the PAH, inulin and renografin clearances are normal in only two-thirds of the cases.

2. When the renograms are normal, and one or another of the clearances is abnormal, it is usually the PAH clearance which proves to be abnormal.

3. Where the renograms are qualitatively abnormal, one or another of these three clearances may be normal. In a high proportion of these, all three clearances may be normal despite the abnormal renogram of either type.

4. Where separate clearance determinations from each kidney are feasible, there is a definite contribution to an understanding of the kidney function which can be contributed by these clearance values, in addition to the qualitative analysis of the renograms. Since it would appear that a renografin-I¹³¹ clearance can be calculated from a renografin-I¹³¹ renogram in a significnat number of cases, it would be important to attempt and record such calculation.

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