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American Journal of Roentgenology, Vol 98, 427-433, Copyright © 1966 by American Roentgen Ray Society

A REACTION FOLLOWING ADMINISTRATION OF MACROAGGREGATED ALBUMIN (MAA) FOR A LUNG SCAN

HOWARD J. DWORKIN M.D.1, JOSEF R. SMITH M.D.2, and FRANCES E. BULL M.D.3

1 At Princess Margaret Hospital, Toronto, Ontario, Canada
2 Associate Professor, Internal Medicine (Medical Chest Section)
3 Assistant Professor, Internal Medicine (Chemotherapy Unit)

A reaction was observed following the administration of macroaggregated albumin (MAA) for a nadionuclide perfusion lung scan in a patient with widespread tumor emboli to the lung. The reaction consisted of faintness, cyanosis, agitation, diaphoresis, tachypnea, a fall in blood pressure and engorged neck veins immediately after intravenous injection of the MAA.

This response suggests that in some patients with pulmonary disease, the safety factor for the MAA lung scan may be decreased and suggestions are presented to minimize the hemodynamic hazards in such individuals.


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Copyright © 1966 by the American Roentgen Ray Society.