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American Journal of Roentgenology, Vol 98, 734-738, Copyright © 1966 by American Roentgen Ray Society

PULMONARY MANIFESTATIONS OF TUBEROUS SCLEROSIS

ROBERT D. MILLEDGE M.D.1, BARRY E. GERALD M.D.1, and WILLIAM J. CARTER M.D.2

1 From the Department of Radiology, University of Arkansas Medical Center, Little Rock, Arkansas
2 From the Department of Pathology, University of Arkansas Medical Center, Little Rock, Arkansas

A patient with the typical clinical, roentgenographic and pathologic features of tuberous sclerosis is reported. Pulmonary involvement was extensive, a rare finding in tuberous sclerosis. The pulmonary involvement is indistinguishable from other causes of interstitial fibrosis. However, bony changes of sclerosis, periosteal new bone formation and cysts are almost invariably associated with the pulmonary lesions. Conversely, intracranial calcifications are rarely associated with pulmonary involvement. The complete clinical syndrome may not be present in all patients with pulmonary involvement.


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Copyright © 1966 by the American Roentgen Ray Society.