AJR Women's Imaging Online
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by BRUNST, V. V.
Right arrow Search for Related Content
PubMed
Right arrow Articles by BRUNST, V. V.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
American Journal of Roentgenology, Vol 99, 482-498, Copyright © 1967 by American Roentgen Ray Society

THE RESPONSE OF THE GILL EPITHELIUM OF THE ADULT AXOLOTL (SIREDON MEXICANUM) TO ROENTGEN RADIATION

V. V. BRUNST D.Sc.1

1 From the Laboratory of Radiobiology, Roswell Park Memorial Institute (New York State Department of Health)

1. The right gills of adult axolotls (Siredon mexicanum), 5 to 6 years old, were locally irradiated with 2,000 r in 10 animals, 4,000 r in 10, and 8,000 r in 10; 10 animals served as untreated controls.

2. Disappearance of the gill filaments is possible in the course of normal development, especially in old axolotls, but was the rule after irradiation. In the present study, normal filaments were never seen after irradiation.

3. The gill filament and the gill epithelium are very sensitive to roentgen radiation, much more so than the skin epithelium. The gill epithelium is one of the most sensitive types of epithelium in the adult axolotl. Even as little as 2,000 r, the smallest dose used, completely disorganized and destroyed the gill filaments and the gill epithelium, which were later replaced with skin epithelium containing many Leydig cells.

4. After irradiation with 8,000 r, giant cells developed in the skin epithelium that replaced the destroyed gill epithelium. Such giant cells were probably caused by moderate radiation damage to the peripheral skin epithelium.

5. Mitosis is extremely rare in the adult axolotl, but it was unusually frequent in close proximity to epithelial cells damaged by irradiation with 8,000 r. Evidently, this observation is an example of radiation stimulation.

6. In the lower vertebrates, and particularly the axolotl, radiation stimulation has previously been observed almost exclusively in young animals; mitosis has never before been observed as a result of radiation stimulation in adult axolotls. The stimulation mitotic activity following irradiation of the gills of adult axolotls in the present study is thus the first case of its kind.

7. A survey of the literature shows that sensitivity and response to radiation differ widely between different types of epithelium, especially skin epithelium and the epithelium of the internal organs, and may even differ widely for a single type of epithelium in young and adult animals.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1967 by the American Roentgen Ray Society.