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American Journal of Roentgenology, Vol 99, 645-659, Copyright © 1967 by American Roentgen Ray Society


RENEWED INTEREST IN GASES FOR CONTRAST ROENTGENOGRAPHY

HENRY BURKO M.D.1 and EUGENE C. KLATFE M.D.1

1 NASHVILLE, TENNESSEE

Four groups of dogs were subjected to intravenous injections of room air, nitrous oxide, and carbon dioxide at injection rates employed clinically in gas contrast roentgenography in order to compare lethal volumes and concentrations. Intravenously injected room air produced death in concentrations similar to those previously reported. Intravenously injected nitrous oxide and carbon dioxide produced death in concentrations and volumes only 3 times greater than air. The volume of carbon dioxide required to produce death was increased 3 times when dogs placed in the left lateral decubitus position were compared with those placed in the supine position. Lethal effects were produced in all dogs injected intravenously with gas at a rate employed in clinical gas roentgenography. Although the absorption coefficients of carbon dioxide and nitrous oxide are 20 times greater than air and oxygen, the safety factor of clinically employed volumes of gas is closer to 3. When introducing relatively large volumes of carbon dioxide and nitrous oxide for intrapleural, intraperitoneal, and retropenitoneal examinations, care should be taken to avoid direct intravascular gas injection, a controlled injection rate should be utilized, fluoroscopic monitoring of the diffusion of the initial volume of gas is advisable, and the left lateral decubitus position should be employed when feasible.

Intravascular injection of 100 cc. of carbon dioxide is a simple and safe method for detecting pericardial effusion. The presence of free right pleural fluid does not necessarily interfere with assessment of right atrial wall thickness. A 3-roentgenogram exposure technique enabled detection of nonuniformity of wall thickness, affording a differentiation between free pericardial fluid and pericardial thickening. The incidence of hepatic vein filling with gas is between 85 to 90 per cent of patients examined and holds promise as a method for roentgen visualization of these structures.

Intrapleural and intraperitoneal carbon dioxide insufilation and nitrous oxide retroperitoneal pneumography are useful and easily performed methods of gas contrast roentgenography.

Gas contrast roentgenography has wide application as an adjunct to conventional roentgenography in solving many clinical problems.


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Copyright © 1967 by the American Roentgen Ray Society.