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Intraductal Papillary Mucinous Tumors of the Pancreas

Thin-Section Helical CT Findings

Yoshihiko Fukukura1, Fumito Fujiyoshi1, Michiro Sasaki1, Hiroki Inoue1, Suguru Yonezawa2 and Masayuki Nakajo1

1 Department of Radiology, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima City, 890-8520, Japan.
2 Department of Second Pathology, Faculty of Medicine, Kagoshima University, Kagoshima City, 890-8520, Japan.



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Fig. 1A. —68-year-old man with benign intraductal papillary mucinous tumor. Helical CT scan shows papilla (arrowheads) bulging into duodenal lumen (straight arrows). Note that papilla is contiguous with main pancreatic duct (curved arrow).

 


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Fig. 2A. —75-year-old man with malignant intraductal papillary mucinous tumor. Helical CT scan shows dilatation of main pancreatic duct (arrow). Pancreatic parenchyma is markedly atrophic.

 


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Fig. 1B. —68-year-old man with benign intraductal papillary mucinous tumor. Helical CT scan shows multilocular cystic lesion (arrowheads) without papillary projections in uncinate process.

 


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Fig. 3A. —71-year-old woman with benign intraductal papillary mucinous tumor with 2-mm papillary neoplasms. Helical CT scan shows multilocular cystic lesion communicating with main pancreatic duct (arrow) in pancreatic tail. Papillary projections corresponding to 2-mm papillary neoplasms in cystic lesion are not seen.

 


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Fig. 4. —65-year-old man with malignant intraductal papillary mucinous tumor. Helical CT scan shows unilocular cystic lesion (arrowhead) in pancreatic head. Communication between dilated main pancreatic duct (arrow) and cystic lesion is equivocal. It is difficult to differentiate intraductal papillary mucinous tumor from other cystic diseases.

 


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Fig. 3B. —71-year-old woman with benign intraductal papillary mucinous tumor with 2-mm papillary neoplasms. Endoscopic retrograde pancreatogram shows slightly dilated main pancreatic duct and simultaneous opacification of cystic lesion in pancreatic tail.

 


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Fig. 1D. —68-year-old man with benign intraductal papillary mucinous tumor. Histologic specimen shows communication (straight arrow) between main pancreatic duct (curved arrow) and cystic lesion (arrowhead) covered by papillary epithelium smaller than 1 mm. (H and E, x1)

 


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Fig. 1C. —68-year-old man with benign intraductal papillary mucinous tumor. Helical CT scan obtained at level directly below that of B shows communication (straight arrow) between dilated main pancreatic duct (curved arrow) and cystic lesion (arrowhead).

 


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Fig. 2C. —75-year-old man with malignant intraductal papillary mucinous tumor. Photograph of excised specimen corresponding to B shows dilated main pancreatic duct filled with 8-mm papillary neoplasms.

 


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Fig. 2B. —75-year-old man with malignant intraductal papillary mucinous tumor. Helical CT scan shows papillary neoplasms (arrowheads) as slightly heterogeneous soft tissue in dilated pancreatic duct. Invasive carcinoma in pancreatic parenchyma is not seen.

 


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Fig. 2D. —75-year-old man with malignant intraductal papillary mucinous tumor. Photomicrograph of histologic specimen corresponding to B and C shows invasive adenocarcinoma components (arrows) in pancreatic parenchyma. (H and E, x5)

 

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