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Prognostic Value of Thoracic FDG PET Imaging After Treatment for Non-Small Cell Lung Cancer

Edward F. Patz, Jr.1, John Connolly2 and James Herndon3

1 Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710
2 Department of Radiology, Rush Medical Center, 1750 Harrison St., Chicago, IL 60612
3 Biometry Division, Duke University Medical Center, Box 3958, Durham, NC 27710



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  		Fig. 1A. —67-year-old man with history of stage I non-small cell lung carcinoma. Posteroanterior chest radiograph shows postoperative changes in right hemithorax. Note slight lobular fullness (arrows) adjacent to surgical clips.

 


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  		Fig. 1B. —67-year-old man with history of stage I non-small cell lung carcinoma. Axial 18F-fluorodeoxyglucose positron emission tomography image in same region as A shows no evidence of recurrence. Patient had no evidence of disease 24 months after resection.

 


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  		Fig. 2A. —56-year-old woman with history of stage II non-small cell lung cancer. Posteroanterior chest radiograph shows minimum heterogeneous opacity (arrow) in left hemithorax after thoracotomy.

 


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  		Fig. 2B. —56-year-old woman with history of stage II non-small cell lung cancer. Axial CT image confirms minimum streaky opacity in left base (arrow).

 


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  		Fig. 2C. —56-year-old woman with history of stage II non-small cell lung cancer. Axial 18F-fluorodeoxyglucose (FDG) positron emission tomography image reveals significant FDG uptake in poorly defined residual opacity (arrows). This patient had recurrent lung cancer.

 


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  		Fig. 3. —Survival curves for patients with positive and negative findings on 18F-fluorodeoxyglucose positron emission tomography (PET) after treatment for non-small cell lung cancer. Solid line = negative PET results, dotted line = positive PET results.

 

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