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Delayed Enhanced CT of Lipid-Poor Adrenal Adenomas

Elaine M. Caoili1, Melvyn Korobkin, Isaac R. Francis, Richard H. Cohan and N. Reed Dunnick

1 All authors: Department of Radiology, University of Michigan Medical Center, 1500 E. Medical Center Dr., Ann Arbor, MI 48109-9723.



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Fig. 1A. 73-year-old woman with history of breast cancer and left adrenal lipid-poor adenoma. Unenhanced CT scan shows left adrenal mass that measured 29 H.

 


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Fig. 1B. 73-old-year woman with history of breast cancer and left adrenal lipid-poor adenoma. Enhanced CT scan shows left adrenal mass that measured 73 H.

 


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Fig. 1C. 73-old-year woman with history of breast cancer and left adrenal lipid-poor adenoma. Delayed enhanced CT scan shows left adrenal mass that measured 44 H. Enhancement washout = 29 H (73 H - 44 H); enhancement = 44 H (73 H - 29 H); percentage enhancement washout = 66% [(enhancement washout / enhancement) = (29 / 44) x 100].

 


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Fig. 2. Bar chart shows there was no significant difference in mean attenuation values between lipid-poor adenomas (dark gray bars) and nonadenomas (light gray bars) before or after contrast enhancement. Mean attenuation values were significantly different between lipid-poor adenomas and lipid-rich adenomas (white bars) for each of three phases.

 


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Fig. 3. Bar chart shows nearly identical enhancement, enhancement washout, and percentage enhancement washout for lipid-rich (white bars) and lipid-poor (dark gray bars) adenomas. Values for nonadenomas (light gray bars) were significantly less than those for both types of adenomas.

 


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Fig. 4. Bar chart shows that unlike true percentage enhancement washout, relative percentage enhancement washout of lipid-poor adenomas (dark gray bars) was significantly lower than that of lipid-rich adenomas (white bars), although still significantly higher than that of nonadenomas (light gray bars).

 

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