Unusual Patterns of Hepatic Steatosis Caused by the Local Effect of Insulin Revealed on Chemical Shift MR Imaging
Jane Sohn1,
Evan S. Siegelman1 and
Andrew W. Osiason2
1
Department of Radiology, University of Pennsylvania Medical School, First
Floor Silverstein, 3400 Spruce St., Philadelphia, PA 19104-4283.
2
Department of Radiology, Hackensack University Medical Center, 30 Prospect
St., Hackensack, NJ 07601.

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Fig. 1A. Focal rim of hepatic steatosis surrounding an insulinoma
metastasis in 27-year-old man. Axial breath-hold spoiled in-phase
gradient-echo image (TR/TE, 250/4.2) shows 12-mm liver mass (straight
arrow). Note phase-encoding artifact from aorta (curved
arrow).
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Fig. 1B. Focal rim of hepatic steatosis surrounding an insulinoma
metastasis in 27-year-old man. Opposed-phase image (250/2.1) corresponding to
A reveals rim of signal loss surrounding lesion indicating focal
hepatic steatosis (arrow).
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Fig. 1C. Focal rim of hepatic steatosis surrounding an insulinoma
metastasis in 27-year-old man. Fat-saturated opposed-phase image (250/2.1)
shows that central tumor (arrow) but not surrounding rim of steatosis
shows enhancement.
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Fig. 1D. Focal rim of hepatic steatosis surrounding an insulinoma
metastasis in 27-year-old man. Intraoperative sonogram reveals same lesion as
that in C with peripheral echogenic rim (arrow).
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Fig. 1E. Focal rim of hepatic steatosis surrounding an insulinoma
metastasis in 27-year-old man. Photomicrograph of histologic specimen shows
three zones: insulinoma metastasis (T), adjacent focal hepatic steatosis
without tumor infiltration (asterisk), and normal hepatic parenchyma
(L). (H and E, x20)
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Fig. 2A. Subcapsular rim of hepatic steatosis in 35-year-old woman
with diabetes mellitus who had insulin in peritoneal dialysate. Unenhanced CT
scan reveals irregular peripheral rim of low attenuation in liver
(asterisks).
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Fig. 2B. Subcapsular rim of hepatic steatosis in 35-year-old woman
with diabetes mellitus who had insulin in peritoneal dialysate. Axial
breath-hold spoiled in-phase gradient-echo MR image (TR/TE, 250/4.2) reveals
irregular peripheral subcapsular rim of higher signal intensity relative to
adjacent hepatic parenchyma (arrows).
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Fig. 2C. Subcapsular rim of hepatic steatosis in 35-year-old woman
with diabetes mellitus who had insulin in peritoneal dialysate. Opposed-phase
image (250/2.1) corresponding to B shows signal loss in subcapsular rim
indicating peripheral hepatic steatosis (asterisks).
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Copyright © 2001 by the American Roentgen Ray Society.