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Clinical Value of Positron Emission Tomography with FDG for Recurrent Ovarian Cancer

Yuji Nakamoto1, Tsuneo Saga1, Takayoshi Ishimori1, Marcelo Mamede1, Kaori Togashi1, Toshihiro Higuchi2, Masaki Mandai2, Shingo Fujii2, Harumi Sakahara3 and Junji Konishi1

1 Department of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine, Kyoto University Hospital, 54 Shogoin-kawahara-cho, Sakyo-Ku, Kyoto, 606-8507 Japan.
2 Department of Gynecology and Obstetrics, Graduate School of Medicine, Kyoto University Hospital, Kyoto, 606-8507 Japan.
3 Department of Radiology, Hamamatsu University School of Medicine, 3600 Handa, Hamamatsu, 431-3192 Japan.



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  		Fig. 1A. —57-year-old woman with recurrent ovarian cancer. Contrast-enhanced CT scan shows two recurrent masses (arrows) in pelvis.

 


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  		Fig. 1B. —57-year-old woman with recurrent ovarian cancer. Position emission tomography scan shows intense uptake in mediastinum (arrow) in addition to those in pelvic region (arrowheads). H and B identify physiologic uptakes in heart and bladder, respectively.

 


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  		Fig. 1C. —57-year-old woman with recurrent ovarian cancer. Thoracic CT scan reveals lymphadenopathy (arrow), suggesting metastases to mediastinal lymph nodes. Chemotherapy was performed before surgery, and size of enlarged nodes was reduced on follow-up CT scan (not shown), suggesting malignant involvement.

 


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  		Fig. 2. —47-year-old woman with recurrent ovarian cancer. Conventional modalities, including CT and sonography, in follow-up period revealed no definite findings of metastasis or recurrence, but coronal (left) and sagittal (right) 18F-fluorodeoxyglucose position emission tomography scans show focal intense uptake adjacent to liver (arrows). Peritoneal dissemination was confirmed at surgery.

 

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