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Lymphoid Hyperplasia of the Stomach

Radiographic Findings in Five Adult Patients

Drew A. Torigian1, Marc S. Levine1, Navdeep S. Gill2, Stephen E. Rubesin1, Franz Fogt3, Christopher F. Schultz4, Emma E. Furth2,5 and Igor Laufer1

1 Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104.
2 Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
3 Department of Pathology and Laboratory Medicine, Presbyterian Medical Center, 51 N. 39th St., Philadelphia, PA 19104.
4 Department of Medicine, Presbyterian Medical Center, Philadelphia, PA 19104.
5 Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.



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  		Fig. 1A. —33-year-old woman with lymphoid hyperplasia of stomach. Supine spot radiograph from double-contrast upper gastrointestinal tract examination shows innumerable tiny round nodules in gastric antrum.

 


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  		Fig. 2. —40-year-old woman with lymphoid hyperplasia of stomach. Left posterior oblique spot radiograph from double-contrast upper gastrointestinal tract barium examination shows innumerable tiny round nodules in gastric antrum. Note similarity to findings in Figure 1A.

 


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  		Fig. 3A. —39-year-old man with lymphoid hyperplasia of stomach. Left posterior oblique spot radiograph from double-contrast upper gastrointestinal tract barium examination shows innumerable tiny round nodules in gastric antrum. Note that many nodules have central umbilications with punctate collections of barium seen en face in lesions.

 


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  		Fig. 1B. —33-year-old woman with lymphoid hyperplasia of stomach. Endoscopic photograph shows multiple nodules in antrum. Arrows denote representative nodules.

 


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  		Fig. 1C. —33-year-old woman with lymphoid hyperplasia of stomach. Photomicrograph of endoscopic biopsy specimen from antrum shows dense lymphocytic infiltrate with central area indicative of early follicle formation (arrow). (H and E, x10)

 


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  		Fig. 3B. —39-year-old man with lymphoid hyperplasia of stomach. Photomicrograph of endoscopic biopsy specimen from antrum shows chronic gastritis with lymphocytic infiltrate. Prominent lymphoid follicle (white arrows) is displacing adjacent glands. Note protrusion of epithelium (black arrows) overlying lymphoid nodule. (H and E, x40)

 


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  		Fig. 1D. —33-year-old woman with lymphoid hyperplasia of stomach. Photomicrograph of biopsy specimen shows multiple curve-shaped bacterial organisms (arrows) compatible with Helicobacter pylori. (Alcian blue, x1000)

 

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