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Calcification in Lymphoma Occurring Before Therapy

CT Features and Clinical Correlation

Sara Apter1,2, Abraham Avigdor2,3, Gabriela Gayer1, Orith Portnoy1, Rivka Zissin2 and Marjorie Hertz1

1 Department of Diagnostic Imaging, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan 52621, Israel.
2 Department of Diagnostic Imaging, Sapir Medical Center, Kfar Saba 44281, Sackler School of Medicine, University of Tel Aviv, Tel Aviv 69978, Israel.
3 Institute of Hematology, Chaim Sheba Medical Center, Tel Hashomer, 52621 Israel.



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  		Fig. 1A. —71-year-old woman with T-cell lymphoblastic lymphoma. Contrast-enhanced CT scan of chest, mediastinal window, shows calcifications (arrow) in center of anterior mediastinal mass.

 


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  		Fig. 1B. —71-year-old woman with T-cell lymphoblastic lymphoma. CT scan obtained at level cranial to A shows discrete calcifications (arrows) surrounding hypodense area in mass.

 


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  		Fig. 2A. —23-year-old woman with mixed cellularity Hodgkin's lymphoma. Unenhanced CT scan of chest, mediastinal window, shows tiny punctate calcifications (arrowheads) at periphery of hypodense area in anterior mediastinal mass.

 


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  		Fig. 2B. —23-year-old woman with mixed cellularity Hodgkin's lymphoma. Posteroanterior (B) and lateral (C) chest radiographs show no calcifications.

 


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  		Fig. 2C. —23-year-old woman with mixed cellularity Hodgkin's lymphoma. Posteroanterior (B) and lateral (C) chest radiographs show no calcifications.

 


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  		Fig. 3A. —42-year-old man with large B-cell lymphoma. Unenhanced CT scan of lower abdomen shows small amorphous calcifications (black arrow) in center of enlarged retroperitoneal nodes adjacent to low-density area (white arrows).

 


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  		Fig. 4. —41-year-old man with diffuse large B-cell lymphoma of right adrenal. Contrast-enhanced CT scan of upper abdomen shows linear calcifications (arrowheads) in right adrenal mass (arrow). Incidental right renal cyst is shown.

 


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  		Fig. 3B. —42-year-old man with large B-cell lymphoma. Contrast-enhanced CT scan obtained at same level as A, 18 months after chemotherapy, shows increase in size of calcifications (black arrow) and decrease in size of nodes (white arrows).

 

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