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Improved Interpretation of Digitized Mammography with Wavelet Processing: A Localization Response Operating Characteristic Study

Maria Kallergi1, John J. Heine, Claudia G. Berman, Marla R. Hersh, A. Pat Romilly and Robert A. Clark

1 All authors: Department of Radiology, College of Medicine, and H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida, 12901 Bruce B. Downs Blvd., Box 17, Tampa, FL 33612-4799.



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  		Fig. 1A. —Right craniocaudal mammogram of 58-year-old woman with relatively low breast density. Original digitized image shows malignant mass and subtle calcification cluster (arrows).

 


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  		Fig. 1B. —Right craniocaudal mammogram of 58-year-old woman with relatively low breast density. Wavelet-enhanced image shows significantly sharper structures, including calcifications, edges, and lines.

 


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  		Fig. 2A. —Left mediolateral oblique mammogram of 45-year-old woman with relatively high breast density. Original digitized image shows malignant lesion associated with subtle microcalcification cluster (arrow).

 


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  		Fig. 2B. —Left mediolateral oblique mammogram of 45-year-old woman with relatively high breast density. Wavelet-enhanced image shows sharper structures and significantly improved contrast even in dense areas of breast.

 


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  		Fig. 3. —Bar diagram of three-reviewer-average values of number of correctly localized cases per finding type (calcification clusters [Ca++] and masses) and pathologic results (benign and malignant) before and after wavelet enhancement. Note that in all cases, findings were more accurately localized on enhanced than on original images. Black bars represent original correctly localized cases, and white bars represent enhanced correctly localized cases.

 

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