Pretransplantation Diagnosis and Staging of Hepatocellular Carcinoma in Patients with Cirrhosis: Value of Dual-Phase Helical CT
Carlos Valls1,
Mònica Cos1,
Juan Figueras2,
Eduard Andía1,
Emilio Ramos2,
Anna Sánchez1,
Teresa Serrano3 and
Jaume Torras2
1 Institut de Diagnòstic per la Imatge, Hospital Universitari de
Bellvitge, L'Hospitalet de Llobregat, Autovia de Castelldefels, Barcelona
08907, Spain.
2 Department of Surgery, Hospital Princeps d'Espanya, Barcelona, Spain.
3 Department of Pathology, Hospital Princeps d'Espanya, Barcelona, Spain.

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Fig. 1A. Hypervascular hepatocellular carcinoma (HCC) in 55-year-old
man with chronic hepatitis C virus infection. Helical CT scan in arterial
phase shows hypervascular lesion (arrow) in segment VIII of
liver.
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Fig. 1B. Hypervascular hepatocellular carcinoma (HCC) in 55-year-old
man with chronic hepatitis C virus infection. Portal phase CT scan obtained at
same level as A shows that lesion (arrow) remains
hyperenhancing. Moderate hyperenhancement of liver parenchyma in periphery of
tumor is evident and consistent with transient hepatic attenuation
difference.
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Fig. 1C. Hypervascular hepatocellular carcinoma (HCC) in 55-year-old
man with chronic hepatitis C virus infection. Corresponding equilibrium phase
image shows slight hypodensity of lesion (arrow) consistent with
HCC.
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Fig. 1D. Hypervascular hepatocellular carcinoma (HCC) in 55-year-old
man with chronic hepatitis C virus infection. Photograph of gross anatomic
specimen confirms well-differentiated HCC (arrowheads).
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Fig. 2A. False-positive finding on helical CT in 41-year-old woman.
Arterial phase CT scan shows small hyperenhancing nodule in segment V of liver
(arrow).
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Fig. 2B. False-positive finding on helical CT in 41-year-old woman.
Corresponding delayed phase CT scan shows that lesion is slightly
hypoattenuating (arrow). These CT findings are highly suggestive of
hepatocellular carcinoma.
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Fig. 2C. False-positive finding on helical CT in 41-year-old woman.
Photomicrograph from histologic examination shows low-grade dysplastic nodule
(arrow).
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Fig. 3A. Understaging of hepatocellular carcinoma on helical CT in
62-year-old man. Axial CT scan in arterial phase at level of left portal vein
shows two hyperenhancing lesions in segment IV and in caudate lobe
(arrowheads) consistent with hepatocellular carcinoma.
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Fig. 3B. Understaging of hepatocellular carcinoma on helical CT in
62-year-old man. Corresponding portal phase CT scan shows that both lesions
remain hyperdense relative to liver parenchyma. Lesion in caudate lobe abuts
right diaphragmatic crus and obliterates focally retrohepatic fat plane
(arrows). These findings were missed preoperatively. At surgery,
gross extrahepatic tumor infiltration was found and complete resection was not
possible.
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Copyright © 2004 by the American Roentgen Ray Society.