MRI Features of Focal Splenic Lesions in Patients with Disseminated Tuberculosis
Adelard I. De Backer1,2,
Filip M. Vanhoenacker1,
Koenraad J. Mortelé3,
Ilse J. Vanschoubroeck4,
Bart L. De Keulenaer4,5 and
Paul M. Parizel1
1 Department of Radiology, Universitair Ziekenhuis Antwerpen, University of
Antwerp, B-2650 Edegem, Belgium.
2 Present address: Department of Radiology, General Hospital Sint-Lucas,
Groenebriel 1, Ghent B-9000, Oost-Vlaanderen, Belgium.
3 Department of Radiology, Division of Abdominal Imaging and Intervention,
Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
4 Department of Internal Medicine, Ziekenhuisnetwerk Antwerpen, B-2060 Antwerp,
Belgium.
5 Present address: Intensive Care Unit, Royal Darwin Hospital, Rocklands, Tiwi,
Northern Territory, Australia.

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Fig. 1A 36-year-old man with miliary tuberculosis, splenic volume of 371
cm3, and tuberculous focal splenic lesions (patient 4 in
Table 1). T2-weighted image
shows multiple nodular lesions (arrows) of variable size that are
hyperintense compared with adjacent splenic tissue.
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Fig. 1B 36-year-old man with miliary tuberculosis, splenic volume of 371
cm3, and tuberculous focal splenic lesions (patient 4 in
Table 1). T1-weighted image
shows lesions (arrow) as hyperintense.
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Fig. 1C 36-year-old man with miliary tuberculosis, splenic volume of 371
cm3, and tuberculous focal splenic lesions (patient 4 in
Table 1). Arterial phase
gadolinium-enhanced T1-weighted image with fat suppression shows peripheral
enhancement (arrows).
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Fig. 1D 36-year-old man with miliary tuberculosis, splenic volume of 371
cm3, and tuberculous focal splenic lesions (patient 4 in
Table 1). Equilibrium phase
image shows lesions with peripheral enhancement and central nonenhancing area
(arrow) and lesion with gradual complete fill-in
(arrowhead). Associated tuberculous lymphadenopathy is noted at liver
hilum.
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Fig. 2A 50-year-old man presenting with signs and symptoms of miliary
tuberculosis as manifestation of AIDS disease. Tuberculous splenic involvement
is characterized by mild splenomegaly and multiple small focal splenic
lesions. Portal venous phase image shows lesions as sharply delineated
hypointense lesions.
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Fig. 2B 50-year-old man presenting with signs and symptoms of miliary
tuberculosis as manifestation of AIDS disease. Tuberculous splenic involvement
is characterized by mild splenomegaly and multiple small focal splenic
lesions. On equilibrium phase image, gradual peripheral contrast enhancement
is noted.
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Fig. 3A 54-year-old man with AIDS with splenomegaly (splenic volume: 876.5
cm3) and splenic lesions diffusely scattered throughout spleen
(patient 3 in Table 1).
T2-weighted (A) and T1-weighted (B) images with fat suppression
show spleen as heterogeneous.
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Fig. 3B 54-year-old man with AIDS with splenomegaly (splenic volume: 876.5
cm3) and splenic lesions diffusely scattered throughout spleen
(patient 3 in Table 1).
T2-weighted (A) and T1-weighted (B) images with fat suppression
show spleen as heterogeneous.
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Fig. 3C 54-year-old man with AIDS with splenomegaly (splenic volume: 876.5
cm3) and splenic lesions diffusely scattered throughout spleen
(patient 3 in Table 1). Dynamic
gadolinium-enhanced images show heterogeneous enhancement of spleen with focal
lesions characterized by peripheral enhancement.
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Fig. 3D 54-year-old man with AIDS with splenomegaly (splenic volume: 876.5
cm3) and splenic lesions diffusely scattered throughout spleen
(patient 3 in Table 1). Dynamic
gadolinium-enhanced images show heterogeneous enhancement of spleen with focal
lesions characterized by peripheral enhancement.
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Copyright © 2006 by the American Roentgen Ray Society.