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Role of MDCT in the Diagnosis of Hepatocellular Carcinoma in Patients with Cirrhosis Undergoing Orthotopic Liver Transplantation

Annalisa Ronzoni1,2, Diana Artioli2, Rosa Scardina3, Luca Battistig4, Ernesto Minola5, Sandro Sironi1,6 and Angelo Vanzulli2

1 School of Medicine, University of Milano-Bicocca, Milan, Italy.
2 Department of Diagnostic Radiology, A. O. Niguarda Ca Granda, Piazza Ospedale Maggiore, Milan 20162, Italy.
3 Department of Diagnostic Radiology, A. O. Vimercate, Milan, Italy.
4 Department of Diagnostic Radiology, Policlinico di Monza, Milan, Italy.
5 Department of Pathology, A. O. Niguarda Ca Granda, Milan, Italy.
6 Department of Diagnostic Radiology, A. O. S. Gerardo Monza, Milan, Italy.


Figure 1
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  		Fig. 1A —64-year-old man with true-positive findings of hepatocellular carcinoma. Arterial phase of MDCT scan shows area of hyperattenuation, giving better lesion conspicuity than B or C.

 

Figure 2
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  		Fig. 1B —64-year-old man with true-positive findings of hepatocellular carcinoma. Venous phase of MDCT scan shows isodensity in relation to liver parenchyma.

 

Figure 3
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  		Fig. 1C —64-year-old man with true-positive findings of hepatocellular carcinoma. Delayed phase of MDCT scan shows hypodense area.

 

Figure 4
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  		Fig. 2A —53-year-old man with true-positive finding of histologically proven hepatocellular carcinoma with hypovascular pattern. Arterial phase of MDCT scan does not depict lesion.

 

Figure 5
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  		Fig. 2B —53-year-old man with true-positive finding of histologically proven hepatocellular carcinoma with hypovascular pattern. Portal phase of MDCT scan shows mildly hypodense area without hyperdense rim.

 

Figure 6
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  		Fig. 2C —53-year-old man with true-positive finding of histologically proven hepatocellular carcinoma with hypovascular pattern. Delayed phase of MDCT scan shows mildly hypodense area without hyperdense rim.

 

Figure 7
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  		Fig. 3A —43-year-old man with false-negative findings. Large nodule of hepatocellular carcinoma was managed with transcatheter arterial chemoembolization in first liver segment. Unenhanced MDCT scan shows hyperdense particles of iodized oil making density inhomogeneous.

 

Figure 8
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  		Fig. 3B —43-year-old man with false-negative findings. Large nodule of hepatocellular carcinoma was managed with transcatheter arterial chemoembolization in first liver segment. Arterial phase of MDCT scan shows lesion enhancement cannot be assessed.

 

Figure 9
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  		Fig. 3C —43-year-old man with false-negative findings. Large nodule of hepatocellular carcinoma was managed with transcatheter arterial chemoembolization in first liver segment. Portal phase of MDCT scan shows lesion washout cannot be assessed.

 

Figure 10
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  		Fig. 3D —43-year-old man with false-negative findings. Large nodule of hepatocellular carcinoma was managed with transcatheter arterial chemoembolization in first liver segment. Delayed phase of MDCT scan shows lesion washout cannot be assessed.

 

Figure 11
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  		Fig. 4A —46-year-old man with false-positive finding of hepatocellular carcinoma. Lesion proved to be regenerative nodule. Arterial phase of MDCT scan shows hyperattenuating nodule.

 

Figure 12
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  		Fig. 4B —46-year-old man with false-positive finding of hepatocellular carcinoma. Lesion proved to be regenerative nodule. Portal phase of MDCT scan shows isodense area.

 

Figure 13
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  		Fig. 4C —46-year-old man with false-positive finding of hepatocellular carcinoma. Lesion proved to be regenerative nodule. Delayed phase of MDCT scan shows isodense area.

 

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