Performance of a Computer-Aided Program for Automated Matching of Metastatic Pulmonary Nodules Detected on Follow-Up Chest CT
Kyung Won Lee1,2,
Miyoung Kim1,
David S. Gierada1 and
Kyongtae T. Bae1,3
1 Mallinckrodt Institute of Radiology, Washington University School of Medicine,
St. Louis, MO.
2 Present address: Department of Radiology, Seoul National University School of
Medicine, Bundang Hospital, Seoul, Korea.
3 Present address: Department of Radiology, University of Pittsburgh School of
Medicine, 200 Lothrop St., Suite 4895, Pittsburgh, PA 15213.
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Fig. 1A —50-year-old man with fewer than 50 metastatic nodules from
renal cell carcinoma and successful matching of well-circumscribed parenchymal
nodule in lingula. Transverse (A) and coronal reformatted (B) CT
images show baseline findings.
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Fig. 1B —50-year-old man with fewer than 50 metastatic nodules from
renal cell carcinoma and successful matching of well-circumscribed parenchymal
nodule in lingula. Transverse (A) and coronal reformatted (B) CT
images show baseline findings.
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Fig. 1C —50-year-old man with fewer than 50 metastatic nodules from
renal cell carcinoma and successful matching of well-circumscribed parenchymal
nodule in lingula. Transverse (C) and coronal reformatted (D) CT
images show follow-up findings. Overall matching rate was 100% (10/10).
Although all nodules had enlarged, number and distribution of nodules were
stable at similar inspiration levels.
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Fig. 1D —50-year-old man with fewer than 50 metastatic nodules from
renal cell carcinoma and successful matching of well-circumscribed parenchymal
nodule in lingula. Transverse (C) and coronal reformatted (D) CT
images show follow-up findings. Overall matching rate was 100% (10/10).
Although all nodules had enlarged, number and distribution of nodules were
stable at similar inspiration levels.
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Fig. 2A —53-year-old man with numerous metastatic nodules from renal
cell carcinoma and unmatched nodule in lingula. Transverse (A) and
coronal reformatted (B) CT images show baseline findings.
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Fig. 2B —53-year-old man with numerous metastatic nodules from renal
cell carcinoma and unmatched nodule in lingula. Transverse (A) and
coronal reformatted (B) CT images show baseline findings.
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Fig. 2C —53-year-old man with numerous metastatic nodules from renal
cell carcinoma and unmatched nodule in lingula. Transverse (C) and
coronal reformatted (D) CT images show follow-up findings. Overall
matching rate was 30% (3/10). Matched volume of interest (VOI) in C and
D is present in wrong place over lung parenchyma without including
nodule. Correct nodule (not shown) that should be matched was located two
sections superior to VOI. Matching rate is low, likely because of substantial
difference in inspiration levels between CT studies. (Inspiration level
difference is not evident in figures, which are screen capture images centered
at matching VOIs.)
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Fig. 2D —53-year-old man with numerous metastatic nodules from renal
cell carcinoma and unmatched nodule in lingula. Transverse (C) and
coronal reformatted (D) CT images show follow-up findings. Overall
matching rate was 30% (3/10). Matched volume of interest (VOI) in C and
D is present in wrong place over lung parenchyma without including
nodule. Correct nodule (not shown) that should be matched was located two
sections superior to VOI. Matching rate is low, likely because of substantial
difference in inspiration levels between CT studies. (Inspiration level
difference is not evident in figures, which are screen capture images centered
at matching VOIs.)
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Fig. 3A —47-year-old woman with numerous metastatic nodules from small
cell lung cancer in right lung and unmatched nodule in superior segment of
left lower lobe. Transverse (A) and coronal reformatted (B) CT
images show baseline findings.
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Fig. 3B —47-year-old woman with numerous metastatic nodules from small
cell lung cancer in right lung and unmatched nodule in superior segment of
left lower lobe. Transverse (A) and coronal reformatted (B) CT
images show baseline findings.
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Fig. 3C —47-year-old woman with numerous metastatic nodules from small
cell lung cancer in right lung and unmatched nodule in superior segment of
left lower lobe. Transverse (C) and coronal reformatted (D) CT
images show follow-up findings. Overall matching rate was 0 (0/10).
Infiltration of lung cancer was markedly increased, with complete collapse of
upper lobe of right lung during interval.
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Fig. 3D —47-year-old woman with numerous metastatic nodules from small
cell lung cancer in right lung and unmatched nodule in superior segment of
left lower lobe. Transverse (C) and coronal reformatted (D) CT
images show follow-up findings. Overall matching rate was 0 (0/10).
Infiltration of lung cancer was markedly increased, with complete collapse of
upper lobe of right lung during interval.
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Copyright © 2007 by the American Roentgen Ray Society.
