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Diagnostic Accuracy of CT-Guided Core Biopsy of Ground-Glass Opacity Pulmonary Lesions

Tae Jung Kim1, Jae-Ho Lee2, Choon-Taek Lee2, Sang Hoon Jheon3, Sook Whan Sung3, Jin-Haeng Chung4 and Kyung Won Lee1

1 Department of Radiology, Seoul National University Bundang Hospital; Seoul National University College of Medicine; and Institute of Radiation Medicine, Seoul National University Medical Research Center; 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do 463-707, Korea.
2 Department of Medicine, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Gyeonggi-do, Korea.
3 Department of Thoracic Surgery, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Gyeonggi-do, Korea.
4 Department of Pathology, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Gyeonggi-do, Korea.


Figure 1
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  		Fig. 1A —CT-guided core biopsy in 60-year-old woman with pure ground-glass opacity (GGO) lesion in right upper lobe. High-resolution CT scan shows 3-cm pure GGO lesion in right upper lobe.

 

Figure 2
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  		Fig. 1B —CT-guided core biopsy in 60-year-old woman with pure ground-glass opacity (GGO) lesion in right upper lobe. CT scan obtained during biopsy shows biopsy needle targeting GGO lesion.

 

Figure 3
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  		Fig. 1C —CT-guided core biopsy in 60-year-old woman with pure ground-glass opacity (GGO) lesion in right upper lobe. Photomicrograph shows gross core biopsy specimen. (H and E, x10)

 

Figure 4
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  		Fig. 1D —CT-guided core biopsy in 60-year-old woman with pure ground-glass opacity (GGO) lesion in right upper lobe. Photomicrograph reveals that alveolar walls are lined by cellular proliferation of atypical pneumocytes with hobnail morphology. No evidence of stromal invasion is seen. Histologic diagnosis of core biopsy was bronchoalveolar carcinoma. Final diagnosis after surgical resection was bronchoalveolar carcinoma, Noguchi type A. (H and E, x200)

 

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