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Fig. 5B. —Measurement of hippocampal volumes using T1-weighted 3D
spoiled gradient-recalled echo sequence in 70-year-old woman at time of
initial diagnosis of mild cognitive impairment. This patient progressed to
dementia over 43-month follow-up period. Comparison of these images with those
shown in Figure 4A,
4B shows possible use of
volumetric imaging to predict subsequent course. (Reprinted with permission
from [28]) Unenhanced coronal
T1-weighted image at region more anterior than that shown in A also
shows decreased volume in head of hippocampus. Boundary used for hippocampal
measurement is outlined in white. Again, size of hippocampus in this patient
is decreased compared with patient who did not progress to dementia, as shown
in Figure 4B.
