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Fig. 7. —Plot shows comparison of ratio of relative cerebral blood
volume measurements in temporoparietal regions to relative cerebral blood
volume measurements in cerebellar cortex (x-axis) with Mini-Mental
State Examination (MMSE) scores (y-axis) in patients with possible or
probable Alzheimer's disease. Comparison shows that, as level of cognitive
functioning decreases, relative cerebral blood volume measurements in these
brain regions also tend to decrease. Note that although distinct separation
between relative cerebral blood volume in patients with normal scores and
those with lowered scores is not seen, clear trend toward lower relative
cerebral blood volume in subjects with lower scores is evident. (Courtesy of
Renshaw P, Belmont, MA)
